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Ganirelix Acetate
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Introduction Ganirelix acetate (or diacetate), sold under the brand names Orgalutran and Antagon among others, is an injectable competitive gonadotropin-releasing hormone antagonist (GnRH antagonist). It is primarily used in assisted reproduction to control ovulation. The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH. Ganirelix is used in fertility treatment to prevent premature ovulation that could result in the harvesting of eggs that are too immature to be used in procedures such as in vitro fertilization.
Sequence C80H113ClN18O13
MW 1570.35
Reference 1. "Orgalutran". European Medicines Agency. Archived from the original on 9 October 2014. Retrieved 11 May 2012.

2. Oberyé J, Mannaerts B, Huisman J, Timmer C (February 2000). "Local tolerance, pharmacokinetics, and dynamics of ganirelix (Orgalutran) administration by Medi-Jector compared to conventional needle injections". Human Reproduction. 15 (2): 245–9. doi:10.1093/humrep/15.2.245. PMID 10655292.

3. Organon Pharmaceuticals USA. "Ganirelix Acetate Injection". DailyMed. Retrieved 11 May 2012.

4. "Orgalutran : EPAR – Scientific Discussion". European Medicines Agency. Archived from the original on 6 May 2014. Retrieved 13 May 2012.
Fields of application