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Leuprorelin Acetate, Ph.Eur./USP/DMF
Cat #
Introduction Leuprorelin, also known as leuprolide, is a manufactured version of a hormone used to treat prostate cancer, breast cancer, endometriosis, uterine fibroids, and early puberty, to perform chemical castration of violent sex offenders, or as part of transgender hormone therapy. It is given by injection into a muscle or under the skin.
Sequence Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt acetate salt
MW 1209.42
Reference D. H. Coy and A. V. Schally, Ann. Clin. Res., 10, 139 (1978)
A. S. Dutta, Drugs Future, 13, 43 (1988)
P. Chrisp and E. M. Sorkin, Drugs & Aging, 1, 487 (1991)
T. Mizutani et al., Int. J. Fertil. Menopaus. Stud., 40, 106 (1995)
A. Imai et al., Int. J. Oncol., 20, 987 (2002)
J. D. Meyer et al., J. Pept. Res., 60, 159 (2002)
E. Castell?n et al., Cancer Invest., 24, 261 (2006)
Merck Index, 14th ed., No. 5457, (2006)
D. Levine et al., J. Reprod. Med., 52, 581 (2007)
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